Influence of micro-environmental pH on the gel layer behavior and release of a basic drug from various hydrophilic matrices

A simple equation for the description of solute release. III. Coupling of diffusion and relaxation

Nikolaos A. Peppas, Jennifer J. Sahlin · International Journal of Pharmaceutics · 1989 · 1.7K citations

Pharmacy, Chemical Engineering, Chemical Kinetics +13

Factors Affecting Mechanism and Kinetics of Drug Release from Matrix-Based Oral Controlled Drug Delivery Systems

Manthena V. S. Varma, Aditya Mohan Kaushal, Alka B. Garg et al. · American Journal of Drug Delivery · 2004 · 240 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +12

Observation of swelling process and diffusion front position during swelling in hydroxypropyl methyl cellulose (HPMC) matrices containing a soluble drug

Paolo Colombo, Ruggero Bettini, Nikolaos A. Peppas · Journal of Controlled Release · 1999 · 218 citations

Pharmacy, Pharmaceutics, Drug Delivery +14

pH-independent release of a weakly basic drug from water-insoluble and -soluble matrix tablets

A. Streubel, Juergen Siepmann, Andrei Dashevsky et al. · Journal of Controlled Release · 2000 · 187 citations

Pharmacy, Pharmaceutics, Pharmacology +16

Swelling and drug release in hydrogel matrices: polymer viscosity and matrix porosity effects

Ruggero Bettini, Paolo Colombo, Gina Massimo et al. · European Journal of Pharmaceutical Sciences · 1994 · 164 citations

Natural Sciences, Materials Science, Pharmaceutics +17