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A neuroactive steroid, dehydroepiandrosterone sulfate, prevents the development of morphine dependence and tolerance via c-fos expression linked to the extracellular signal-regulated protein kinase

Neuroactive SteroidSignal TransductionEndocrine MechanismMedicineMorphine DependencePhysiologyNeuroendocrine MechanismHormonal ReceptorNeuropharmacologyNeuroscienceGlucocorticoidEndocrinologyPharmacologySteroid MetabolismC-fos Expression