Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.

C. Richard Boland, Stephen N. Thibodeau, Stanley R. Hamilton et al. · PubMed · 1998 · 4.1K citations

Life Sciences, Genetics, Oncology +17

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Richard Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell · 1993 · 2.9K citations

Life Sciences, Genetics, Oncology +14

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Medicine, Genetics, Molecular Genetics +17

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC☆

Hans F. A. Vasen, Peter H. Watson, Jukka‐Pekka Mecklin et al. · Gastroenterology · 1999 · 2.5K citations · Full text

Life Sciences, Genetics, Oncology +17

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

Hans F. A. Vasen, Jukka‐Pekka Mecklin, P. Meera Khan et al. · Diseases of the Colon & Rectum · 1991 · 2.2K citations

Medicine, Genetics, Oncology +17