NMDA receptor antagonists ketamine and PCP have direct effects on the dopamine D2 and serotonin 5-HT2 receptors—implications for models of schizophrenia

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Bita Moghaddam, Barbara W. Adams, Anita Verma et al. · Journal of Neuroscience · 1997 · 1.8K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Reversal of Phencyclidine Effects by a Group II Metabotropic Glutamate Receptor Agonist in Rats

Bita Moghaddam, Barbara W. Adams · Science · 1998 · 1K citations

Medicine, Neuroscience, Pharmacology +17

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

J.S. Kim, H. H. Kornhuber, W. Schmid‐Burgk et al. · Neuroscience Letters · 1980 · 698 citations

Medicine, Neuroscience, Psychiatry +14

Psychedelic Effects of Ketamine in Healthy Volunteers 

Andrew T. Bowdle, Allen D. Radant, Deborah S. Cowley et al. · Anesthesiology · 1998 · 371 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

KETAMINE INFUSIONS: PHARMACOKINETICS AND CLINICAL EFFECTS

Jan Idvall, I. Ahlgren, K. F. Aronsen et al. · British Journal of Anaesthesia · 1979 · 310 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +11