Synlett · 1997 · 18 citations · 0 references
Natural SciencesChemistryMicrobiologyPolymer ChemistryAntibacterial AgentsAntibacterial TherapyAntibacterial Drug DevelopmentAntimicrobial PolymersAntimicrobial PropertiesCovalent InteractionsEscherichia ColiNovel Antibacterial AgentsQuaternary Ammonium Compounds
A series of polyammonium species, each bearing two to ten cationic sites within the covalent structure, have been synthesized. For these species quaternary ammonium sites are located in a linear array at regular intervals along a "string" backbone with free-floating anions. The polycationic species exhibit antibacterial activity using strains of E. coli.