Concepedia

Chimeric VEGFRs are activated by a small-molecule dimerizer and mediate downstream signalling cascades in endothelial cells

Emma L. KNIGHT, Andrea J. WARNER, Anthony Maxwell, Sally A. Prigent

Oncogene · 2000 · 21 citations · 43 references

DOI

Concepts

References

43

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

David W. M. Leung, George Cachianes, Wun-Jing Kuang et al. · Science · 1989 · 5K citations

, , +10

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

Peter Carmeliet, Valérie Ferreira, Georg Breier et al. · Nature · 1996 · 4.1K citations

, , +14

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al. · Nature · 1995 · 3.9K citations

, , +8

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

K. Jin Kim, Bing Li, Jane Winer et al. · Nature · 1993 · 3.6K citations

, , +14

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein et al. · Nature · 1995 · 2.6K citations

, , +13