Fuzhengpaidu granule Regulates Immune Activation Molecules CD38 and human leukocyte antigen-D related on CD4+ and CD8+ T Cells in Patients with Acquired immunodeficiency syndrome/human immunodeficiency virus

Abstract

HIV/AIDS patients exhibited an immune activation profile following FZPDG treatment. A potential mechanism of action for FZPDG appears to lie in its ability to up-regulate CD38 and HLA-DR levels on CD4+ T cells, and down-regulate them on CD8+ cells, thereby modulating immune activation of CD4+and CD8+T cells.