Down syndrome biochemical markers and screening for preeclampsia at first and second trimester: correlation with the week of onset and the severity

Abstract

Down syndrome biochemical markers levels are altered in those patients who subsequently developed preeclampsia and may be a useful screening test for preeclampsia. Inhibin-A is the most predictive marker and correlates with the severity of subsequent preeclampsia and inversely with the week of occurrence of preeclampsia.