Concepedia

Development of a high-throughput method for the determination of itraconazole and its hydroxy metabolite in human plasma, employing automated liquid–liquid extraction based on 96-well format plates and LC/MS/MS

Constantinos Kousoulos, Georgia Tsatsou, Constantinos Apostolou, Yannis Dotsikas, Yannis L. Loukas

Analytical and Bioanalytical Chemistry · 2005 · 44 citations · 18 references

DOI

Concepts

References

18

The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds

Ryan P. Bonfiglio, Richard C. King, Timothy Olah et al. · Rapid Communications in Mass Spectrometry · 1999 · 922 citations

, , +10

Semi-automated 96-well liquid–liquid extraction for quantitation of drugs in biological fluids

Nanyan Zhang, Keith L. Hoffman, Wenlin Li et al. · Journal of Pharmaceutical and Biomedical Analysis · 2000 · 76 citations

, , +8

Quantitative analysis of simvastatin and its β-hydroxy acid in human plasma using automated liquid–liquid extraction based on 96-well plate format and liquid chromatography-tandem mass spectrometry

Nanyan Zhang, Amy Y. Yang, John Rogers et al. · Journal of Pharmaceutical and Biomedical Analysis · 2003 · 69 citations

, , +16

Rapid and sensitive high performance liquid chromatographic method for the determination of itraconazole and its hydroxy-metabolite in human serum

Paul O. Gubbins, Bill J. Gurley, Jason L. Bowman · Journal of Pharmaceutical and Biomedical Analysis · 1998 · 63 citations

, , +11

Quantitation of SU11248, an oral multi-target tyrosine kinase inhibitor, and its metabolite in monkey tissues by liquid chromatograph with tandem mass spectrometry following semi-automated liquid–liquid extraction

Simona Barattè, S. Sarati, E. Frigerio et al. · Journal of Chromatography A · 2003 · 60 citations

, , +17