Clinical Toxicology · 2008 · 10 citations · 6 references
PharmacyPharmacologyToxicologyHeavy Metal PoisoningHeavy Metal ToxicologyPoisoning DiagnosisChelation TherapyMercury PoisoningMercury ToxicologyMetal ToxicityChelation Therapy For MercuryChelator Adverse EffectsIntravenous Bolus InjectionMercury Poisoning ManagementMercury Poisoning TreatmentMercury-induced Renal ToxicityRenal Elimination KineticsRenal Elimination Pathways
INTRODUCTION: Although several cases of i.v. injection of metallic mercury have been reported, it still remains an uncommon event. CASE REPORT: A 34-year-old male came to hospital because complaining of pleuritic chest pain. X-ray showed radio dense punctate lesions in both lung fields, as well as around both elbows. Mercury concentration in blood (140 microg/L) and urine (320 microg/L) from the patient were significantly elevated, compared with the reference concentrations of < or = 2.0 mug/L mercury in blood and urine. The course of renal elimination of mercury and the mercury concentration in whole blood during 5 months of chelation therapy with sodium 2,3-dimercapto-1-propanesulfonate (Dimaval) were monitored. Furthermore, the time-course of mercury in scalp hair from the patient was determined. CONCLUSION: We report a case of probable consecutive i.v. administration of metallic mercury.
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