Biodynamic Organothiophosphates of Pyridine: Synthesis and Bioactivity

Abstract

The biological importance and practical significance of thiophosphates and pyridine nucleus prompted us to synthesize organothiophosphate of pyridine. In this regard, we have synthesized new series of such derivatives adopting the synthetic methodology, which we have evolved in our laboratory using cycloiminium derivatives of pyridine as starting material and PCl3 as phosphorylating agent. These representatives were also tested for their insecticidal activity against a notorious polyphagus insect Helicoverpa armigera.