MPTP <scp>A</scp>nimal <scp>M</scp>odel of <scp>P</scp>arkinsonism: <scp>D</scp>opamine <scp>C</scp>ell <scp>D</scp>eath or <scp>O</scp>nly <scp>T</scp>yrosine <scp>H</scp>ydroxylase <scp>I</scp>mpairment? – <scp>A S</scp>tudy <scp>U</scp>sing <scp>PET I</scp>maging, <scp>A</scp>utoradiography, and <scp>I</scp>mmunohistochemistry in the <scp>C</scp>at

Abstract

These data suggest that MPTP toxicity impairs efficiently TH and that such an effect is not necessarily accompanied by significant reduction of dopamine transporter seen with in vitro or in vivo [(11) C]PE2I binding.