New England Journal of Medicine · 1977 · 110 citations · 48 references
MedicineImmunologyInfectious DiseasesImmunopathologyPediatric Infectious DiseasesPulmonologyCongenital InfectionsImmunocompromised Host InfectionsImmunosuppressionPulmonary InfectionsRespiratory DiseaseRespiratory InfectionsImmunosuppressive Drug TherapyPneumocystis InfectionSystemic Immunosuppressive TherapyTransplant-associated Infections
BY the middle of the 20th century, Pneumocystis carinii pneumonitis had not been recognized in North America. Yet within the past two decades the prevalence has increased to the point that several hundred cases occur annually in the United States. The emergence of this infectious disease is probably related directly to the increased use of immunosuppressive therapy for diseases of somewhat unrelated causes. Organ-transplant recipients, patients with cancer and children with congenital immune deficiency disorders constitute the majority of patients at risk for the disease. In such cases, referred to here as the "child-adult type," the pneumonitis is an acute, . . .
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Successful Chemoprophylaxis for<i>Pneumocystis carinii</i>Pneumonitis
Walter T. Hughes, Shirley Kuhn, Subhash Chaudhary et al. · New England Journal of Medicine · 1977 · 693 citations
PNEUMOCYSTIS CARINII INFECTION
Barbara A. Burke, Robert A. Good · Medicine · 1973 · 279 citations