Design and Investigation of a Series of Rhodamine-Based Fluorescent Probes for Optical Measurements of pH

Quinn A. Best, Ruisong Xu, Matthew E. McCarroll, Lichang Wang, Daniel J. Dyer

Organic Letters · 2010 · 141 citations · 21 references

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Abstract

A series of structurally similar fluorescent probes (1-4), synthesized from rhodamine B, were designed to optically measure pH. Each probe had a unique "off-on" response as the solution went from basic to acidic. Probes 1-3 exhibited a spirocyclic quenching of the pyronin B fluorophore, whereas probe 4 was quenched by PET from the amine moiety.

References

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