Regression of multiple viral warts in a human immunodeficiency virus-infected patient treated by triple antiretroviral therapy

Abstract

Human papillomavirus‐induced viral warts may cause therapeutic problems, especially in human immunodeficiency virus (HIV)‐infected patients. We report a 34‐year‐old homosexual man who, after testing HIV‐positive in January 1998, suffered from multiple, extensive viral warts, particularly on his hands (Fig. 1) and upper lip. He received oral antiretroviral therapy for 2 years, initially with didanosine, stavudine and efavirenz. The efavirenz was changed to abacavir in June 1999. The medication was taken irregularly until November 2000. Following 4 months of closely supervised subsequent therapy, a nearly total regression of the viral warts was seen (Fig. 2), accompanied by a significant improvement in immune status.