Enhancement of Sexual Motivation in Sexually Naive Male Mice by Eurycoma longifolia

Abstract

Eurycoma longifolia was preliminary investigated for aphrodisiac property on sexually naive male mice using both the modified runway-choice and open field methods. The animals were conditioned to seek, either an estrous female, a measure of right choice for sexual motivation or a male mouse, a measure of wrong choice, within two minutes. However, male mice which failed to response within the stipulated period were considered as having no choice. Oral administration of 0.5 g/kg daily of different fractions of E. longifolia viz., chloroform, methanol, water and butanol resulted in an enhancement of the sexual motivation of the animals after three days post-treatment and the effect was more prominent after eight days post-treatment.