Intraischemic Hypothermia Attenuates Neutrophil Infiltration in the Rat Neocortex after Focal Ischemia-Reperfusion Injury

Abstract

These findings demonstrate that intraischemic hypothermia attenuates the inflammatory response to transient focal ischemia in the pericore region, i.e., the region spared from infarction under hypothermic conditions. The findings raise the possibility that a reduction in the inflammatory response after ischemia/reperfusion contributes to the neuroprotective effects of hypothermia.