Canadian Journal of Chemistry · 1971 · 16 citations · 0 references
Thirteen MembersGeneral Preparative MethodHeterocyclicDiversity-oriented SynthesisAromatic AminesOrganic ChemistryPharmacologyEnantioselective Synthesis
The reaction of ω-bromoalkyl isothiocyanates with aromatic amines served as a general preparative method for homologous 2-arylimino-1,3-thiaazacycloalkanes. Rings containing seven to thirteen members were prepared in this way. The isothiocyanates and some of the thiaazacycloalkanes had anthelmintic activity.