Ghrelin does not mediate the somatotroph and corticotroph responses to the stimulatory effect of glucagon or insulin‐induced hypoglycaemia in humans

Abstract

Ghrelin does not mediate the GH and ACTH responses to glucagon or to the ITT. In fact, ghrelin levels are not modified at all by glucagon and transiently decrease during the ITT. These findings support the assumption that ghrelin does not play a major role in the physiological control of somatotroph and corticotroph function.