A SKIN REACTION TO QUININ

Abstract

Idiosyncrasies of certain persons to such drugs as quinin, strychnin, iodoform and atropin are not at all uncommon, and many cases have been reported in which serious symptoms have resulted from the use of these drugs by such persons. For a number of years I have been known to be hypersensitive to quinin. The first indication of this sensitiveness was observed after I had taken the drug for an attack of grip, the effects being manifested by a body rash and intense itching of the skin. Several times since, it has been taken in relatively small doses and has invariably caused a reddening of the skin and severe itching. In some of the noninfectious diseases due to anaphylaxis, skin reactions have been found of practical value, and as idiosyncrasies to drugs are believed to be due to this phenomenon, it was considered of interest to try a skin reaction for