Concepedia

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

Ronit I. Yarden, Sherly Pardo-Reoyo, Magda Sgagias, Kenneth H. Cowan, Lawrence C. Brody

Nature Genetics · 2002 · 481 citations · 25 references

DOI

Concepts

References

25

Mitotic and G <sub>2</sub> Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

Cheng‐Yuan Peng, Paul R. Graves, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

Linkage of ATM to Cell Cycle Regulation by the Chk2 Protein Kinase

Satomi Matsuoka · 1998 · 1.3K citations

, , +17

Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Yolanda Sánchez, Calvin Wong, Richard S. Thoma et al. · Science · 1997 · 1.3K citations

, , +17

Is a p53-Regulated Inhibitor of G2/M Progression

Heiko Hermeking, Christoph Lengauer, Kornélia Polyák et al. · Molecular Cell · 1997 · 1.2K citations · Full text

, , +17

Distinct Roles for Cyclin-Dependent Kinases in Cell Cycle Control

Sander van den Heuvel, Ed Harlow · Science · 1993 · 1.1K citations

, , +13