Familial occurrence of multiple intracranial aneurysms

Abstract

✓ A 48-year-old man and his 66-year-old mother had multiple intracranial saccular aneurysms visualized by angiography or verified at autopsy. Histological examination of the arteries at the base of the brain in the case autopsied showed a caterpillar tread-like appearance (“Raupenketten Elastica”) of the internal elastic lamina, which may indicate thinning of the elastic lamina and deserve consideration as a causative factor in the development of intracranial saccular aneurysms.