Polymorphisms associated with thrombophilia and vascular homeostasis and the timing of menarche and menopause in 728 white women

Abstract

We identified various genetic and personal history parameters influencing age at natural menopause and the risk of undergoing premenopausal hysterectomy. To the best of our knowledge, we present the largest study to date determining SNPs as contributors to the genetic control of the timing of natural and surgical menopause.