Zur Kenntnis der sesquiterpenoiden C₁₂‐Ketone des ätherischen Öls von <i>Vetiveria zizanioides</i> (L.) Nash

Abstract

Abstract Two new C 12 ‐ketones, (+)‐(1 S , 10 R )‐1,10‐dimethylbicyclo[4.4.0]dec‐6‐en‐3‐one ( 5 ) and (+)‐(6 S , 10 S )‐6,10‐dimethylbicyclo[4.4.0]dec‐1‐en‐3‐one ( 6 ), have been isolated from Reunion vetiver oil ( Vetiveria zizanioides (L.) Nash). Structure and absolute configuration of 5 were established by a four‐step synthesis from (+)‐isonootkatone ((+)‐α‐vetivone) ( 1 ). The structure of 6 followed from its spectroscopic properties and was confirmed by direct comparison with an authentic racemic sample. The absolute configuration of 6 was established by chemical correlation with (+)‐α‐eudesmol ( 13 ).