Thiourea-phosphonium salts from amino acids: cooperative phase-transfer catalysts in the enantioselective aza-Henry reaction

Dongdong Cao, Zhuo Chai, Jiaxing Zhang, Zhengqing Ye, Hua Xiao, Hongyu Wang, Jinhao Chen, Xiaoyu Wu, Gang Zhao

Chemical Communications · 2013 · 120 citations · 46 references

Concepts

Abstract

New chiral bifunctional thiourea-phosphonium salts have been developed based on natural amino acids as highly efficient phase-transfer catalysts in the enantioselective aza-Henry reaction.

References

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