Using a novel plug flow reactor for the in situ, simultaneous, monitoring of SAXS and WAXD during crystallisation from solution

H. Alison, Roger J. Davey, John Garside, Michael J. Quayle, G. J. T. Tiddy, David T. Clarke, Gareth R. Jones

Physical Chemistry Chemical Physics · 2003 · 25 citations · 1 references

Concepts

Abstract

The design and application of a novel plug flow crystalliser is described. Simultaneous collection of SAXS and WAXD during the nucleation and crystal growth of a small organic molecule from solution is reported. Preliminary data imply the separation of a non-diffracting phase prior to the appearance of crystalline solid.

References

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