Concepedia

Antifungal triazole alcohols: A comparative analysis of structure-activity, structure-teratogenicity and structure-therapeutic index relationships using the Multiple Computer-Automated Structure Evaluation (Multi-CASE) methodology

Gilles Klopman, Dmitri Ptchelintsev

Journal of Computer-Aided Molecular Design · 1993 · 22 citations · 6 references

DOI

Concepts

References

6

Artificial intelligence approach to structure-activity studies. Computer automated structure evaluation of biological activity of organic molecules

Gilles Klopman · Journal of the American Chemical Society · 1984 · 428 citations

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Pharmacokinetic evaluation of UK-49,858, a metabolically stable triazole antifungal drug, in animals and humans

Michael Humphrey, S. Jevons, Michael H. Tarbit · Antimicrobial Agents and Chemotherapy · 1985 · 366 citations · Full text

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MULTICASE 1. A Hierarchical Computer Automated Structure Evaluation Program

Gilles Klopman · Quantitative Structure-Activity Relationships · 1992 · 314 citations

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Computer simulation of physical-chemical properties of organic molecules. 1. Molecular system identification

Gilles Klopman, M. McGonigal · Journal of Chemical Information and Computer Sciences · 1981 · 55 citations

, , +10

Causality in structure—activity studies

Gilles Klopman, Alexander N. Kalos · Journal of Computational Chemistry · 1985 · 53 citations

, , +17