Immunoglobulin <scp>A</scp> and immunoglobulin <scp>G</scp> antibodies against β‐lactoglobulin and gliadin at age 1 associate with immunoglobulin <scp>E</scp> sensitization at age 6

Abstract

Increased IgA or IgG against BLG or gliadin at age 1 was associated with IgE sensitization at age 6. We suggest that an enhanced antibody response to food antigens reflects mucosal tolerance aberrancies, e.g., altered microbiota and/or increased gut permeability, which is later seen as sensitization to allergens.