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Understanding the structure–activity and structure–selectivity correlation of cyclic guanine derivatives as phosphodiesterase-5 inhibitors by molecular docking, CoMFA and CoMSIA analyses

Molecular PharmacologyStructure–selectivity CorrelationBiochemistryMedicinePharmacologyRational Drug DesignMechanism Of ActionCyclic Guanine DerivativesMolecular DockingMolecular ModelingInhibitory ActivityDrug Discovery