Droperidol Lengthens Cardiac Repolarization due to Block of the Rapid Component of the Delayed Rectifier Potassium Current - Concepedia

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Droperidol Lengthens Cardiac Repolarization due to Block of the Rapid Component of the Delayed Rectifier Potassium Current

121

Citations

42

References

1999

Year

Benoît Drolet, Shetuan Zhang, Dominic Deschênes, Jimmy Rail, Sylvie Nadeau, Zhengfeng Zhou, Craig T. January, Jacques Turgeon

Journal of Cardiovascular Electrophysiology

Abstract

Potent block of I(K)r by droperidol is likely to underlie QT prolongation observed in patients treated at therapeutic plasma concentrations (10 to 400 nmol/L) of the drug.

References

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