Publication | Closed Access
A Toxicopathologic Study in Animals After Brief Single Exposures to Hydrogen Fluoride
30
Citations
6
References
1963
Year
PathologyComparative ToxicologyToxicological MechanismEnvironmental HealthToxicologyToxicological AspectClinical ChemistryPublic HealthAllergyLiver PhysiologyToxicopathologic StudyHydrogen FluoridePoisoningHuman ExposureEcotoxicologyExperimental ToxicologyHuman Sensory LevelsPharmacologyBrief Single ExposuresPhysiologyForensic ToxicologyVeterinary ScienceEnvironmental ToxicologySingle ExposuresLc50 ValuesMedicine
Abstract The LC50 values for single exposures to HF were found to be 4970, 2690, 2040, and 1310 ppm for rats exposed respectively for periods of 5, 15, 30 and 60 minutes. Rats, dogs and rabbits were exposed also to concentrations of 6% to 50% of the LC50 values for rats. Signs of intoxication and pathology are described. Renal and hepatic lesions were noted. Human sensory levels may be more sensitive than animal studies in estabishing tolerable levels for brief human exposures.
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