Surfactant Protein D Expression in Chronic Rhinosinusitis Patients and Immune Responses In Vitro to <i>Aspergillus</i> and <i>Alternaria</i> in a Nasal Explant Model

Abstract

We report for the first time the expression of SP-D in both diseased and normal nasal mucosa. SP-D expression in CRS patients is up-regulated by fungal allergens in an in vitro model. These results may provide potential novel therapy for treatment of CRS.