Concepedia

Design, synthesis, and application of tartaric acid derived N-spiroquaternary ammonium salts as chiral phase-transfer catalysts

Mario Waser, Katharina Gratzer, Richard Herchl, Norbert Müller

Organic & Biomolecular Chemistry · 2011 · 54 citations · 32 references

Open access

Abstract

A novel class of tartaric acid-derived N-spiro quaternary ammonium salts was synthesised starting from known TADDOLs. These compounds were found to catalyse the asymmetric α-alkylation of glycine Schiff bases with high enantioselectivities and in good yields.

References

32

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Chemical Engineering, Chiral Phase-transfer Catalysis, Engineering +9