Hepatocyte growth factor and c-Met promote dendritic maturation during hippocampal neuron differentiation via the Akt pathway

The establishment of polarity by hippocampal neurons in culture

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Life Sciences, Neurobiology, Neuroscience +17

RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

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Control of Dendritic Arborization by the Phosphoinositide-3′-Kinase–Akt–Mammalian Target of Rapamycin Pathway

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A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.

James G. Christensen, Randall Schreck, Jon Burrows et al. · PubMed · 2003 · 497 citations

Medicine, Oncology, Pharmacology +15

Amplification of <i>MET</i> may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

Gromoslaw A. Smolen, Raffaella Sordella, Beth Muir et al. · Proceedings of the National Academy of Sciences · 2006 · 484 citations · Full text

Medicine, Cancer Biology, Oncology +17