An Efficient Route to 3‐Amidylindoles <i>via</i> a Palladium‐ Catalyzed Tandem Reaction of 2‐Alkynylanilines with Isocyanides

Guanyinsheng Qiu, Chen Chen, Liangqing Yao, Jie Wu

Advanced Synthesis & Catalysis · 2013 · 65 citations · 36 references

Concepts

Abstract

Abstract A palladium‐catalyzed reaction of 2‐alkynylaniline, isocyanides, and silver acetate is described, leading to 3‐amidylindoles in moderate to good yields. During the process, five new bonds are formed with high reaction efficiency in one‐pot procedure.

References

36