TIN‐PROTOPORPHYRIN: A POTENT PHOTOSENSITIZER OF BILIRUBIN DESTRUCTION

Abstract

Abstract— Tin(IV)‐protoporphyrin chloride, a proposed chemotherapeutic agent for prevention of neonatal hyperbilirubinemia, is a potent photosensitizer of bilirubin destruction in vitro at visible wavelengths (410, 540, 580 nm). We speculate that the drug may have phototoxic effects in vivo if it accumulates in light‐accessible tissues.