<i>N</i>¹‐Selective Oxidative CN Coupling of Azoles with Pyrroles Using a Hypervalent Iodine Reagent

Abstract

Abstract A method for coupling azoles with pyrroles and related compounds using a hypervalent iodine reagent has been developed. The oxidative coupling to produce the CN bond directly from CH and NH bonds is attractive in view of sustainable chemistry by avoiding prefunctionalization of the substrates. Notably, the reactions are found to be N 1 ‐selective at the azoles and tolerant of a broad range of substrates and functional groups.