Angewandte Chemie International Edition · 2011 · 119 citations · 19 references
Life SciencesBiochemistryMicrobiologyDrug DiscoveryMetabolismMetabolomicsMass Spectrometry-based MetabolomicsMetabolite AnnotationMetabolite IdentificationMetabolite ProfilingMetabolomics Data AnalysisMicrobial MetabolomicsMetabolite Pattern AnalysisSecondary Metabolite ProfilingUnknown Metabolite CharacterizationUntargeted Metabolomics Analysis
Come to the fore: The novel myxobacterial metabolite myxoprincomide is easy to overlook in the complex LC-MS data recorded for the metabolome of Myxococcus xanthus DK1622, such that advanced analytical techniques were needed for its discovery. By enhancing genomics-based natural products research with powerful analytical tools for in-depth metabolome mining, two additional such “hidden” metabolites have been uncovered. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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