Pyridinolysis of Diethyl Phosphinic Chloride in Acetonitrile

Abstract

Table 1. Second-Order Rate Constants (k2 10 2 /M -1 s -1 ) of the Reactions of Et2P(=O)Cl (2O) with XC5H4N in MeCN at 45.0 o C X 4-MeO 4-Me 3-Me H 3-Ph 3-MeO 3-Cl 3-Ac 4-Ac 3-CN 4-CN k2 10 2 96.1 2.3 49.9 1.4 27.1 0.3 18.8 0.4 11.0 0.3 8.29 0.05 2.00 0.04 1.94 0.05 1.27 0.02 0.500 0.012 0.498 0.019