Association of the Glu298Asp Polymorphism in the Endothelial Nitric Oxide Synthase Gene with Essential Hypertension Resistant to Conventional Therapy

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

David S. Bredt, Paul M. Hwang, Charles E. Glatt et al. · Nature · 1991 · 2.4K citations

Life Sciences, Biochemistry, Molecular Biology +9

Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors

Jeannette Vásquez‐Vivar, Balaraman Kalyanaraman, Pavel Martásek et al. · Proceedings of the National Academy of Sciences · 1998 · 1.5K citations

Life Sciences, Biochemistry, Physiology +11

ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM

Marek W. Radomski, Richard Palmer, Salvador Moncada · The Lancet · 1987 · 1.4K citations

Medicine, Cell Biology, Hematology +10

Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene

Philip A. Marsden, Henry H. Heng, Stephen W. Scherer et al. · Journal of Biological Chemistry · 1993 · 878 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

T⁻⁷⁸⁶→C Mutation in the 5′-Flanking Region of the Endothelial Nitric Oxide Synthase Gene Is Associated With Coronary Spasm

Masafumi Nakayama, Hirofumi Yasue, Michihiro Yoshimura et al. · Circulation · 1999 · 779 citations · Full text

Medicine, Genetics, Molecular Genetics +15