Researches on the Intestinal Protozoa of Monkeys and Man. IV. An experimental study of the<i>Histolytica</i>-like species of<i>Entamoeba</i>living naturally in Macaques

Abstract

Nine attempts to infect kittens directly with E. histolytica macacorurn by means of amoebae ( per anum ) or cysts ( per os ) in the faeces of 2 M. sinicus (Polo and Susanna) and 1 M. rhesus (Jacko), were wholly unsuccessful. Four similar experiments with cysts ( per os ) from another M. sinicus (Bonar) gave 2 positive (Kittens 28 and 31) and 2 negative results. Attempts to transmit strains of E. histolytica macacorum from one species of Macacus to another have been uniformly successful. A strain ( D. ) of E. histolytica , derived from a man suffering from acute amoebic dysentery, has been cultivated in vitro continuously for 5½ years. (i) The fact has been confirmed that strains of E. histolytica which, when newly isolated, are infective for kittens, may lose this infectivity after continued cultivation in vitro .