Concepedia

Microbial transformation of racemic hydantoins to <scp>D</scp>‐amino acids

Roberto Olivieri, E. Fascetti, Luciana Gabriella Angelini, Lukas Degen

Biotechnology and Bioengineering · 1981 · 163 citations · 11 references

DOI

Concepts

Abstract

Abstract It has been shown that resting cells of Agrobacterium radiobacter catalyze a sequence of two stereospecific hydrolytic reactions leading to the complete transformation of racemic hydantoins to D ‐amino acids. This report describes some properties of this new biocatalyst and its potential application for the production of some D ‐amino acids, which are used as intermediates in the preparation of semisynthetic penicillin and cephalosporins.

References

11

The Use of Cyanate for the Determination of NH2-terminal Residues in Proteins

George R. Stark, Derek G. Smyth · Journal of Biological Chemistry · 1963 · 474 citations · Full text

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Studies on continuous enzyme reactions. IV. Preparation of a DEAE‐sephadex–aminoacylase column and continuous optical resolution of acyl‐<scp>DL</scp>‐amino acids

Tetsuya Tosa, Takao Mori, N Fuse et al. · Biotechnology and Bioengineering · 1967 · 118 citations

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Engineering analysis of continuous production of <scp>L</scp>‐aspartic acid by immobilized <i>Escherichia coli</i> cells in fixed beds

Tadashi Sato, Takao Mori, Tetsuya Tosa et al. · Biotechnology and Bioengineering · 1975 · 110 citations

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Microbial transformation of hydantoins to N-carbamyl-D-amino acids

Sho Takahashi · Journal of Fermentation Technology · 1979 · 93 citations

, , +11

Enzymatic conversion of N carbamoyl-d-amino acids to d-amino acids

Roberto Olivieri, E. Fascetti, Luciana Gabriella Angelini et al. · Enzyme and Microbial Technology · 1979 · 77 citations

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