Gd-Loaded Liposomes as <i>T</i>₁, Susceptibility, and CEST Agents, All in One

Abstract

Gd-loaded nonspherical liposomes represent a new family of MRI agents that show contrast-enhancing ability upon applying different image acquisition modes. In fact they can act either as T 1 - or T 2 - or CEST- agents. For the first time a Gd complex is endowed with detectable shift reagent properties.