Reduktion von Oximen mit Natriumboranat in Gegenwart von Übergangsmetallverbindungen

Abstract

Reduction of Oximes with Sodium Borohydride in the Presence of Transition Metal Compounds The reduction of oximes with sodium borohydride in the presence of NiCl 2 · 6 H 2 O and MoO 3 was investigated. The combination of NaBH 4 with NiCl 2 · 6 H 2 O converted the unsaturated oximes through exhaustive reduction into saturated amines (Table 1). The C = C double bond remains preserved if the reduction is carried out in the presence of MoO 3 (Table 2). The stereo‐chemistry of the reduction in the presence of NiCl 2 · 6 H 2 O is distinctivly different from that of MoO 3 .