Intraaccumbens injections of substance P, morphine and amphetamine: effects on conditioned place preference and behavioral activity

A psychomotor stimulant theory of addiction.

Roy A. Wise, Michael A. Bozarth · Psychological Review · 1987 · 2.7K citations

Medicine, Neuroscience, Pharmacology +17

Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway.

Rainer Spanagel, A. Herz, Toni S. Shippenberg · Proceedings of the National Academy of Sciences · 1992 · 1K citations

Life Sciences, Neuroscience, Pharmacology +16

Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens.

Francesco E. Pontieri, Gianluigi Tanda, G. Di Chiara · Proceedings of the National Academy of Sciences · 1995 · 868 citations

Medicine, Neuroscience, Pharmacology +17

Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity

Annick Pijnenburg, Wiel Honig, J.A.M. van der Heyden et al. · European Journal of Pharmacology · 1976 · 567 citations

Life Sciences, Neurobiology, Neuroscience +16

Destruction of dopaminergic nerve terminals in nucleus accumbens: Effect on d-amphetamine self-administration

William H. Lyness, N.M. Friedle, Kenneth E. Moore · Pharmacology Biochemistry and Behavior · 1979 · 458 citations

Life Sciences, Neurobiology, Neuroscience +16