Concepedia

Azasteroids: Potent inhibitors of insect molting and metamorphosis

James A. Svoboda, M. J. Thompson, W. E. Robbins

Lipids · 1972 · 48 citations · 10 references

DOI

Concepts

Abstract

Abstract Based on previous structure‐activity studies, four new azasteroids were synthesized and tested in several species of insects. These compounds, which are the most potent azasteroid inhibitors of insect growth and development tested to date, affect the hormone‐regulated processes of molting and metamorphosis.

References

10

Ecdysones and synthetic analogs: Molting hormone activity and inhibitive effects on insect growth, metamorphosis and reproduction

W. E. Robbins, J. N. Kaplanis, T. J. Shortino et al. · Steroids · 1970 · 81 citations

, , +14

Desmosterol, an intermediate in dealkylation of β-sitosterol in the tobacco hornworm

James A. Svoboda, M. J. Thompson, W. E. Robbins · Life Sciences · 1967 · 64 citations

, , +9

The inhibitive effects of azasterols on sterol metabolism and growth and development in insects with special reference to the tobacco hornworm

James A. Svoboda, W. E. Robbins · Lipids · 1971 · 52 citations

, , +17

Conversion of Beta Sitosterol to Cholesterol Blocked in an Insect by Hypocholesterolemic Agents

James A. Svoboda, W. E. Robbins · Science · 1967 · 51 citations

, , +17

Desmosterol as a common intermediate in the conversion of a number of C28 and C29 plant sterols to cholesterol by the tobacco hornworm

James A. Svoboda, W. E. Robbins · Cellular and Molecular Life Sciences · 1968 · 45 citations

, , +15