Critical Care · 2013 · 17 citations · 2 references
Veterinary MedicineImmunologyInfectious DiseasesInflammationInnate ImmunitySepsisAcute InflammationCytokine BiologyInflammation In Infectious DiseaseInflammatory Cell ResponsesSepsis PathophysiologySepsis PrognosisAcute-phase MediatorsProinflammatory MediatorsSepsis PathologySepsis-associated Cytokine DysregulationSepsis-associated Cytokine ResponseSepsis-associated Inflammation
IL-6, a proinflammatory cytokine, is synthesized from fibro-blasts, T lymphocytes, endothelial cells and monocytes. It serves as an important mediator during the acute phase response to inflammation in sepsis. We hypothesized that the plasma IL-6 is correlated with mortality and severity scores in critically ill patients with sepsis.
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Stephan Harbarth, K Holecková, Céline Froidevaux et al. · American Journal of Respiratory and Critical Care Medicine · 2001 · 908 citations