Science · 1982 · 123 citations · 102 references
Life SciencesDevelopmental BiologyMolecular BiologyEmbryogenesisEmbryologyGene ExpressionChromatinEarly Embryonic DevelopmentEarly Embryo DevelopmentEmbryo EpigeneticsLineage-specific GenesMarine Invertebrate EmbryologyMaternal Contribution To Embryogenesis
Research on the early development of the sea urchin offers new insights into the process of embryogenesis. Maternal messenger RNA stored in the unfertilized egg supports most of the protein synthesis in the early embryo, but the structure of maternal transcripts suggests that additional functions are also possible. The overall developmental patterns of transcription and protein synthesis are known, and current measurements describe the expression of specific genes, including the histone genes, the ribosomal genes, and the actin genes. Possible mechanisms of developmental commitment are explored for regions of the early embryo that give rise to specified cell lineages, such as the micromere-mesenchyme cell lineage.
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Are snRNPs involved in splicing?
Michael R. Lerner, John A. Boyle, Stephen M. Mount et al. · Nature · 1980 · 1.2K citations
Spicule Formation by Isolated Micromeres of the Sea Urchin Embryo
Kayo Okazaki · American Zoologist · 1975 · 311 citations · Full text
Structural gene sets active in embryos and adult tissues of the sea urchin
Glenn A. Galau, William H. Klein, Mark M. Davis et al. · Cell · 1976 · 295 citations