Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Bin Zhao, Xiaomu Wei, Weiquan Li et al. · Genes & Development · 2007 · 3.2K citations · Full text

Life Sciences, Cell Biology, Genetics +17

Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals

Jixin Dong, Georg Feldmann, Jianbin Huang et al. · Cell · 2007 · 2.4K citations · Full text

Life Sciences, Biology, Entomology +9

The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP

Jianbin Huang, Shian Wu, Jose Barrera et al. · Cell · 2005 · 1.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

René H. Medema, Geert J.P.L. Kops, Johannes L. Bos et al. · Nature · 2000 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +14

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

Walter Brogiolo, Hugo Stocker, Tomoatsu Ikeya et al. · Current Biology · 2001 · 1.3K citations · Full text

Life Sciences, Biology, Endocrinology +15