Concepedia

Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase

Vikas Patil, Manoj Kale, Anandkumar Raichurkar, Brahatheeswaran Bhaskar, Dwarakanath Prahlad, Meenakshi Balganesh, Santosh Nandan, P. Shahul Hameed

Bioorganic & Medicinal Chemistry Letters · 2014 · 30 citations · 9 references

DOI

Concepts

References

9

The sulfonylurea herbicide sulfometuron methyl is an extremely potent and selective inhibitor of acetolactate synthase in Salmonella typhimurium.

Robert A. LaRossa, John V. Schloss · Journal of Biological Chemistry · 1984 · 390 citations · Full text

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Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase

Jennifer A. McCourt, Siew Siew Pang, J. King-Scott et al. · Proceedings of the National Academy of Sciences · 2006 · 367 citations · Full text

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Inhibitors of branched-chain amino acid biosynthesis as potential antituberculosis agents

J A Grandoni, Prosbová Marta, John V. Schloss · Journal of Antimicrobial Chemotherapy · 1998 · 168 citations

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Elucidating the Specificity of Binding of Sulfonylurea Herbicides to Acetohydroxyacid Synthase

Jennifer A. McCourt, Siew Siew Pang, Luke W. Guddat et al. · Biochemistry · 2005 · 123 citations

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New herbicidal derivatives of 1,2,4‐triazolo [1,5‐a] pyrimidine

William A. Kleschick, Mark J. Costales, Joseph E. Dunbar et al. · Pesticide Science · 1990 · 86 citations

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